Ming Singer’s work is about bridging the current deeply-held divide between sentience and reason. It focuses on the pragmatic role of sentient experience and its unceasing and inseparable interplay with the exercise of reason. Part I of the book deals first with the need for synthesizing the hitherto separate “truth-finding” knowledge traditions: the third-personal scientific-technological, and the first-personal humanistic-wisdom tradition. A conceptual framework for a mind reality is then proposed. Drawing from the unifying natural laws in current physical and biological sciences, the mind reality is portrayed in terms of one interlocking open dynamic system with both a manifested and a covert aspect. In this entire system, each individual mind constantly “co-creates” and “co-evolves” with other collective or group minds at various levels. It is also presumed that the basic unit of interaction in the mind reality is thought or intent. Supporting evidence from psychology, parapsychology and the ancient perennial philosophies is presented. The second part of the book addresses the pragmatic consequences of the proposed mind reality. At the individual level, it is argued that sentient experience can serve the function of guiding, affirming and fostering an individual’s life’s work. A selection of existing first-personal accounts is presented to illustrate this point. At the collective level, the current dominant collective thought of “new capitalism” has the unfortunate consequences for humanity’s sense of freedom, education and morality. Such consequences pertain to the “exteriorization” and the “deconstruction” of the intrinsic self and intrinsic values. To avoid this to happen, a collective effort at changing consciousness becomes necessary: the core task lies with the closure of the reason and sentience divide.